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Description

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Cells were cultured for 4 days with or without hemin (1 M) and pyruvate (1 mM)

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Este proceso es especialmente relevante en tejidos con alta demanda energtica, como: Msculo esqueltico Corazn (miocardio) Sistema nervioso Sistema inmune Por eso, alteraciones en la disponibilidad o el metabolismo de la carnitina pueden asociarse a sntomas como: Fatiga intensa y/o fatigabilidad Intolerancia al esfuerzo Debilidad muscular Disfuncin cognitiva (niebla mental) Sensacin de mala recuperacin tras actividad 2) Funciones biolgicas clave 2.1 Transporte de cidos grasos (entrada mitocondrial y -oxidacin) La carnitina participa en el transporte carnitina (sistema CPT), que permite que los cidos grasos de cadena larga crucen la membrana mitocondrial interna para ser oxidados

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